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PHYSICIANS SHOULD EXERCISE CAUTION WHEN CONSIDERING THE USE OF HUMIRA IN PATIENTS WITH A HISTORY OF RECURRENT INFECTION OR UNDERLYING CONDITIONS WHICH MAY PREDISPOSE THEM TO INFECTIONS, OR PATIENTS WHO HAVE RESIDED IN REGIONS WHERE TUBERCULOSIS AND HISTOPLASMOSIS ARE ENDEMIC (see PRECAUTIONS - Tuberculosis and ADVERSE REACTIONS - Infections).
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Flovent HFA and Flovent Diskus: No dosage adjustment necessary.
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The study was approved by the Human Ethics Review Board of our institution, and parents provided written informed consent.
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The primary efficacy end point was the first severe asthma exacerbation based on systemic glucocorticoid use for 3 days or hospitalization.
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